Cardiovascular
VASCULARIZATION CHALLENGE
[breadcrumb]
cardiovascular
sub-challenges
- Creation of multiscale and multiphenotype vascular networks in cubic centimeter volumes.
- Perfusion of engineered vascular networks. Perfusion must also include energy and oxygen rich perfusate.
- Understand the cross talk between cardiomyocytes and vascular cells, and leverage these interactions to rapidly obtain more comprehensive vascular networks.
- Understand relationship between cardiomyocyte functional parameters and vasculature: when and how much vascularization is required for cardiomyocytes conduction and contraction?
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