New OrganLiver Prize

Liver Prize

Our First Prize Rallies Scientists Worldwide to Bioengineer a Liver.

The New Organ Liver Prize will award $1,000,000 to the first team
that creates a bioengineered replacement for the native liver of a
large mammal, enabling it to recover in the absence of native
function and survive three months with a normal lifestyle.
Future prizes will cover the heart, lungs, and kidney.


The New Organ Liver Prize will be
evaluated by a judging committee
of well-qualified, independent and
impartial experts. The $1 million
challenge is international and
open to participants globally.

The first registered team to meet
the required guidelines by Decem-
ber 31, 2018, will win the award.

the RulesPDF Icon

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Prize Registration


To begin the registration process,
download and complete the Intent
to Participate form. Teams wishing
to participate must submit the Intent
to Participate form to the Methuselah
Foundation a minimum of seven
months before beginning trials.


Upon official recognition, teams
will be asked to submit their Team
Agreement, $1,000 early-bird
registration fee (early-bird rate
available until July 31, 2013), and
Executive Summary at least six
months before beginning trials.


Please complete the form and
submit it to

Intent to participate form>

Team Trial Application documents
must be submitted to the judging
committee at least three months
before trials begin, on a date agreed
to with the judging committee.


New Organ's goal is to advance the day when no one dies for lack of a healthy organ, and the New Organ Liver Prize is our first step toward that goal.

Around the world, millions of people need replacement organs, and many die before finding a suitable donor. In the United States, the wait list has skyrocketed while the number of available organs has stayed relatively flat. Even those fortunate enough to find an organ in time face serious medical difficulties, often for the rest of their lives.

The growing field of regenerative medicine offers many potential solutions, but it is drastically underfunded compared to more established areas of medicine. We're using an incentive prize challenge to spur innovation in whole organ regeneration, engineering, and preservation and to help draw popular attention to this vital cause.

In order to put regenerative medicine and tissue engineering on the map as game-changing solutions to organ disease and the global organ shortage, we wanted to create a powerful focal point, and prizes are perfect for this.

Well-executed incentive prizes have launched entire industries in the past, such as the Orteig Prize won by Charles Lindbergh in 1927, which transformed U.S. aviation. Among other things, good prizes can attract new capital to seemingly intractable problems, motivate top minds and non-traditional players, galvanize public demand, force regulatory reform, encourage smart risk taking, and help transcend perceived constraints.

Right now, the New Organ Liver Prize is worth $1 million. We are actively seeking partners to increase that amount.

Many, many people have been affected by organ disease and the organ shortage crisis, if not directly, then indirectly through the suffering of friends or family members. What's more, we believe that breakthroughs in whole organ tissue engineering will act as a catalyst for accelerating regenerative technologies as a whole, and regenerative medicine is going to make all of our lives dramatically better. This belief was a key motivator for us in designing the New Organ Liver Prize.

Our initial prize, the New Organ Liver Prize, is the first in a series of challenges and awards to incentivize tissue engineering solutions for all of the complex solid organs, including the heart, kidney, lungs, and pancreas. We're also currently exploring a prize focused on organ preservation with the Organ Preservation Alliance, a coalition incubated by Singularity University Labs.

Absolutely. The New Organ Liver Prize is open to qualified teams wishing to participate from anywhere in the world.

The Methuselah Foundation (New Organ's host charity) does not claim any rights on IP produced by the prize teams.

If you haven't already, sign up as an organ donor. New Organ exists to usher in broader, longer-term solutions to the organ crisis, but donor organ transplants still save tens of thousands of lives every year right now. Take a few minutes to register at

You can support New Organ directly by donating here, as well as sharing via social media.

No. The full $1 million prize will be awarded to the first registered team that can create a bioengineered replacement for the native liver of a large mammal, enabling the host to recover in the absence of native liver function and survive three months with a normal lifestyle.

To register, you must submit an Intent to Participate form to the Methuselah Foundation at least seven months before beginning trials. You can download the Intent to Participate form (PDF) here, and send it to

Once accepted, teams will later be required to submit a Team Agreement, a $1,000 registration fee (early-bird rate available until July 31, 2013), an Executive Summary, and a series of Team Trial Application documents to the judging committee.

The New Organ Liver Prize will be judged by a panel of five to seven independent, highly-qualified experts. We're in the process of forming the judging committee, which will be solely responsible for evaluating compliance with all prize guidelines and rules, and will have final authority in awarding the prize.

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